Gboxin

• UNSPSC Description:

  Gboxin is an oxidative phosphorylation (OXPHOS) inhibitor that targets glioblastoma. Gboxin inhibits the activity of F0F1 ATP synthase. Antitumour activity[1].

• Target Antigen:

  ATP Synthase; Mitochondrial Metabolism; Oxidative Phosphorylation

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Gboxin.html

• Purity:

  98.23

• Solubility:

  DMSO : 32.5 mg/mL (ultrasonic)|H2O : 10 mg/mL (ultrasonic)

• Smiles:

  O=C(O[C@H]1[C@H](C(C)C)CC[C@@H](C)C1)CN2C(CC)=[N+](C)C3=CC=CC=C23.[Cl-]

• Molecular Weight:

  392.96

• References & Citations:

  [1]Shi Y, et al. Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. Nature. 2019 Mar;567(7748):341-346.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  2101315-36-8