Pomalidomide-PEG2-Tos

Pomalidomide-PEG2-Tos

• CAS Number: 2599846-07-6
• UNSPSC Description: Pomalidomide-PEG2-Tos is an E3 ligase ligand-linker conjugates, composed of a cereblon ligand and two-unit PEG linker[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pomalidomide-peg2-tos.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOS(C4=CC=C(C=C4)C)(=O)=O)=O
• Molecular Weight: 515.54
• References & Citations: [1]Su S, et al. Potent and Preferential Degradation of CDK6 via Proteolysis Targeting Chimera Degraders. J Med Chem. 2019 Aug 22;62(16):7575-7582.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported