WDR5-IN-6

WDR5-IN-6

• CAS Number: 326901-92-2
• UNSPSC Description: WDR5-IN-6 is a WDR5 inhibitor, targeting to WBM site. WDR5-IN-6 inhibits cell proliferation of neuroblastoma cell lines with potent anti-tumor activity. WDR5-IN-6 shows high synergy with OICR-9429 (HY-16993), a WDR5 inhibitor targeting to WIN site. WDR5-IN-6 can be used for reasearch in neuroblastoma[1].
• Target Antigen: WDR5
• Type: Reference compound
• Related Pathways: Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/wdr5-in-6.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=S(C1=CC(Cl)=CC=C1Cl)(N2C=NC3=C2C=CC=C3)=O
• Molecular Weight: 327.19
• References & Citations: [1]Han QL, et al. Discovery, evaluation and mechanism study of WDR5-targeted small molecular inhibitors for neuroblastoma. Acta Pharmacol Sin. 2023 Apr;44(4):877-887.
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported