CUDC-427

CAT: 0804-HY-15835-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-15835-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CUDC-427 is a potent second-generation pan-selective IAP antagonist, used for treatment of various cancers.
CAS Number
[1446182-94-0]
Product Name Alternative
GDC-0917
UNSPSC
12352005
Target
IAP
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/CUDC-427.html
Purity
99.32
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C([C@H](CCC1)N1C([C@H](C2CCCCC2)NC([C@H](C)NC)=O)=O)NC3=C(C4=CC=CC=C4)N=C(C5=NC=CO5)S3
Molecular Formula
C29H36N6O4S
Molecular Weight
564.70
References & Citations
[1]Wong H, et al. Learning and confirming with preclinical studies: modeling and simulation in the discovery of GDC-0917, an inhibitor of apoptosis proteins antagonist. Drug Metab Dispos. 2013 Dec;41 (12) :2104-13.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1

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Alternative Products

CatalogName
MBS5754747CUDC-427
A20943-10CUDC-427 10mg
A20943-1CUDC-427 1mg
A20943-2CUDC-427 2mg
A20943-5CUDC-427 5mg
A20943-25CUDC-427 25mg
A20943-50CUDC-427 50mg
A20943-100CUDC-427 100mg
205468GDC-0917 (CUDC-427)
A20943-10mM-DCUDC-427 10mM * 1mL in DMSO

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