CUDA

CAT: 0804-HY-121538-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-121538-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
CUDA is a potent inhibitor of soluble epoxide hydrolase (sEH), with IC50s of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively[1]. CUDA selectively increases peroxisome proliferator-activated receptor (PPAR) alpha activity. CUDA may be valuable for the research of cardiovascular disease[2].
CAS Number
[479413-68-8]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Epoxide Hydrolase; PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-anti-virus
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/cuda.html
Purity
99.83
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(NC1CCCCC1)NCCCCCCCCCCCC(O)=O
Molecular Formula
C19H36N2O3
Molecular Weight
340.50
Precautions
H302, H315, H319, H335
References & Citations
[1]Morisseau C, et al. Structural refinement of inhibitors of urea-based soluble epoxide hydrolases. Biochem Pharmacol. 2002 May 1;63 (9) :1599-608.|[2]Fang X, et al. Activation of peroxisome proliferator-activated receptor alpha by substituted urea-derived soluble epoxide hydrolase inhibitors. J Pharmacol Exp Ther. 2005 Jul;314 (1) :260-70.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARα

Related Products

CatalogName
HY-10223-01CUDC-101
HY-15835-01CUDC-427

Alternative Products

CatalogName
M26131-01CUDA
T206289-01CUDA disodium
MBS1165937Recombinant Dictyostelium discoideum Putative transcriptional regulator cudA (cudA), partial

Popular Products