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PHT-427-d4

CAT: 0804-HY-W719359Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W719359Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PHT-427-d4 is the deuterium labeled PHT-427. PHT-247 is an inhibitor of the pleckstrin homology (PH) domain of Akt, and it is also an inhibitor of PDPK1 with Kis of 2.7 μM and 5.2 μM and for Akt and PDPK1, respectively.
UNSPSC
12352005
Target
Akt; Apoptosis; Isotope-Labeled Compounds
Related Pathways
Apoptosis; Others; PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
O=S(C1=C(C([2H])=C(C([2H])=C1[2H])CCCCCCCCCCCC)[2H])(NC2=NN=CS2)=O
Molecular Formula
C20H27D4N3O2S2
Molecular Weight
413.63
References & Citations
[1]Meuillet EJ, et al. Molecular pharmacology and antitumor activity of PHT-427, a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor. Mol Cancer Ther. 2010 Mar;9 (3) :706-17.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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