Rbin-1

• Description :

  Rbin-1 is a potent, reversible, and specific chemical inhibitor of eukaryotic ribosome biogenesis. Rbin-1 inhibits the ATPase with GI50 of 136 nM. Rbin-1 is a potent and selective chemical inhibitor of Midasin (Mdn1) .

• Product Name Alternative :

  Ribozinoindole-1

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319, H320

• Target :

  Phosphatase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/Rbin-1.html

• Purity :

  99.85

• Solubility :

  DMSO : ≥ 31 mg/mL

• Smiles :

  C=C(C)CSC1=NN=C2C(NC3=C2C=CC=C3)=N1

• Molecular Formula :

  C13H12N4S

• Molecular Weight :

  256.33

• Precautions :

  H315, H319, H320

• References & Citations :

  [1]Kawashima SA, et al. Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis. Cell. 2016 Oct 6;167 (2) :512-524.e14.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [328023-11-6]