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Nicotianamine

CAT: 0804-HY-121858-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-121858-01Size:500 µg
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Description
Nicotianamine can be isolated from the leaves of Nicotiana Tabacum L.. Nicotianamine is a key biosynthetic precursor of phytosiderophores. Nicotianamine is an iron chelating agent and can promote the transport of iron. Nicotianamine is an angiotensin-converting enzyme (ACE) inhibitor with IC50 values of 76 nM and 59 nM for rhACE2 and rhACE, respectively. Nicotianamine is vital in metal nutrition and metal homeostasis of flowering plants[1][2].
CAS Number
34441-14-0
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Angiotensin-converting Enzyme (ACE)
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/nicotianamine.html
Smiles
OC([C@@H](N)CCN[C@H](C(O)=O)CCN1[C@@H](CC1)C(O)=O)=O
Molecular Formula
C12H21N3O6
Molecular Weight
303.31
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Bouazaoui M, et al. Synthesis and biological activity of nicotianamine and analogues. Adv Exp Med Biol. 2009;611:555-7. |[2]Takahashi S, et al. Nicotianamine is a novel angiotensin-converting enzyme 2 inhibitor in soybean. Biomed Res. 2015;36 (3) :219-24.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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