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(±) -PPCC (hemioxalate)

CAT: 0804-HY-108514Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-108514Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(±) -PPCC hemioxalate is a compound that has the ability to regulate the activity of the sigma-1 receptor. (±) -PPCC hemioxalate can selectively bind sigma-1 protein (s1), and then activate s1 receptor leading to dissociation of s1-BIP complex to regulate ER-mitochondrial calcium signaling, which plays an important role in cell bioenergy and cell survival. (±) -PPCC hemioxalate can be used to study sigma-1 receptors in cocaine addiction, forgetting, pain, depression, Alzheimer's disease, stroke, and cancer[1].
CAS Number
932736-91-9
UNSPSC
12352005
Target
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/racemic-ppcc-hemioxalate.html
Smiles
O=C([C@@]1(C2=CC=C(C)C=C2)[C@@H](CN3CCC(C4=CC=CC=C4)(O)CC3)C1)OC.O=C(O)C(O)=O.[0.5]
Molecular Formula
C24H29NO3.0.5C2H2O4
Molecular Weight
424.23
References & Citations
[1]Sarpietro M G, et al. DSC investigation of the effect of the new sigma ligand PPCC on DMPC lipid membrane[J]. International Journal of Pharmaceutics, 2014, 469 (1) : 88-93.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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