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Kv3.1 modulator 2

CAT: 0804-HY-163018-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-163018-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Kv3.1 modulator 2 (compound 4) is a Kv3.1 channels modulator with an EC50 value of 68 nM[1].
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/kv3-1-modulator-2.html
Purity
99.79
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1NC2=CN=C(N=C2N1C3=C(C(Cl)=C(N=C3)OC4=C5C(C)(COC5=CC=C4)C)C)C
Molecular Formula
C22H20ClN5O3
Molecular Weight
437.88
References & Citations
[1]Yun-Ting Chen, et al. Identification, structural, and biophysical characterization of a positive modulator of human Kv3.1 channels. Proc Natl Acad Sci U S A. 2023, 120, 42. |[2]Yun-Ting Chen, et al. Identification, structural, and biophysical characterization of a positive modulator of human Kv3.1 channels. Proc Natl Acad Sci U S A. 2023, 120, 42.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported