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EGFR-IN-119

CAT: 0013-GTR19237864-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19237864-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-119 (Compound 5l) is a potent EGFR inhibitor (IC50 = 84.3 nM) with cytotoxic activity in A549 lung cancer cells (IC50 = 1.34 μM) . It downregulates EGFR, KRAS, and MAP2K expression and exhibits antioxidative effects by reducing ROS and hyperpolarizing mitochondrial membrane potential, supporting its use in oncology research for in vitro mechanistic studies.
Field of Research
Cardiovascular Research, Cell Biology, Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.

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