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Catenin beta Antibody

CAT: 0013-GTR18793509Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18793509Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Our Anti-Catenin beta sheep polyclonal primary antibody detects human, mouse, and rat Catenin beta, and is affinity-purified. It is validated for use in ICC, IHC-Frozen, WB.
Product Name Alternative
Catenin beta-1; Beta-catenin; CTNNB1; CTNNB; _-Catenin
UniProt
P35222
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide (C-QSYLDSGIHSGATTTAPSL) corresponding to the amino acid region 28-46 of human Catenin beta coupled to carrier protein KLH. This antibody was designed to detect the active form of Catenin beta . The antibody exhibits a strong preference for dephosphorylated beta catenin protein by western blot but the antibody may show cross reactivity with phosphorylated catenin beta under certain conditions.
Target
Catenin beta
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution
WB: 2 μg/mL; ICC: 4 μg/mL
Form
Lyophilized
Molecular Weight
86-92 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IHC, WB
Host or Source
Sheep
Preservative
Lyophilized from 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, and 0.05 % sodium azide.
Isotype
IgG

UniProtKB · P35222

Catenin beta-1

CTNB1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P35222
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CTNNB1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K1L7, Q8NEW9, Q8NI94, Q9H391
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationGlycoproteinPhosphoproteinS-nitrosylationUbl conjugation

Molecular function

Activator

Biological process

Cell adhesionHost-virus interactionNeurogenesisTranscriptionTranscription regulationWnt signaling pathway

Cellular component

Cell junctionCell membraneCell projectionCytoplasmCytoskeletonMembraneNucleusSynapse

Coding sequence diversity

Chromosomal rearrangement

Disease

Disease variantIntellectual disability

Domain

Repeat

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