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Beta Catenin Antibody

CAT: 0013-GTR18573183Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18573183Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Beta Catenin is a dual function protein, regulating the coordination of cell-cell adhesion and gene transcription. In humans, the CTNNB1 protein is encoded by the CTNNB1 gene. In Drosophila, the homologous protein is called armadillo. Beta catenin is a subunit of the cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. It is a member of the catenin protein family and homologous to gamma-Catenin, also known as plakoglobin. Beta-Catenin is widely expressed in many tissues. In cardiac muscle, it localizes to adherens junctions in intercalated disc structures, which are critical for electrical and mechanical coupling between adjacent cardiomyocyte. [Wiki]
UniProt
P35222
Reactivity
Human, Mouse
Immunogen
A C-terminal 100 amino acid segment from chicken beta-Catenin was used as the immunogen for the Beta Catenin antibody.
Clonality
Monoclonal
Clone
5H10
Conjugation
Unconjugated
Purification
Protein G affinity chromatography
Dilution
Flow cytometry: 0.5-1ug/million cells, Immunofluorescence: 1-2ug/ml, Western blot: 0.5-1ug/ml, Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the Beta Catenin antibody to be determined by the researcher.
Tested Applications
FACS, IF, IHC-P, WB
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1, kappa

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