CTPB

• Description :

  CTPB is a good activator of p300 histone acetyl transferase (HAT) enzyme[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319

• Target :

  Histone Acetyltransferase

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/CTPB.html

• Purity :

  99.0

• Solubility :

  DMSO : 62.5 mg/mL (ultrasonic)

• Smiles :

  O=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)C2=C(CCCCCCCCCCCCCCC)C=CC=C2OCC

• Molecular Formula :

  C31H43ClF3NO2

• Molecular Weight :

  554.13

• Precautions :

  H302, H315, H319

• References & Citations :

  [1]Sivanandam M, et al. Investigation of activation mechanism and conformational stability of N- (4-chloro-3-trifluoromethyl-phenyl) -2-ethoxybenzamide and N- (4-chloro-3-trifluoromethyl-phenyl) -2-ethoxy-6-pentadecyl-benzamidein the active site of p300 histone acetyl transferase enzyme by molecular dynamics and binding free-energy studies. J Biomol Struct Dyn. 2018 Oct 9:1-38.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  CBP/p300

• CAS Number :

  [586976-24-1]