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NecroX-5

CAT: 0804-HY-104015-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-104015-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NecroX-5 is a derivative of the NecroX, reduces intracellular calcium concentration, and possesses anti-inflammatory and anti-cancer activity.
CAS Number
[1383718-29-3]
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/NecroX-5.html
Purity
98.16
Solubility
DMSO : 170 mg/mL (ultrasonic)
Smiles
O=S1(CCN(CC2=CC3=C(NC(C4=CC=CC=C4)=C3)C(NCC5CCOCC5)=C2)CC1)=O.CS(=O)(O)=O.CS(=O)(O)=O
Molecular Formula
C27H39N3O9S3
Molecular Weight
645.81
References & Citations
[1]Park JH, et al. NecroX-5 prevents breast cancer metastasis by AKT inhibition via reducing intracellular calcium levels. Int J Oncol. 2017 Jan;50 (1) :185-192.|[2]Thu VT, et al. NecroX-5 exerts anti-inflammatory and anti-fibrotic effects via modulation of the TNFα/Dcn/TGFβ1/Smad2 pathway in hypoxia/reoxygenation-treated rat hearts. Korean J Physiol Pharmacol. 2016 May;20 (3) :305-14.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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MBS5753567NecroX-5
M11590-01Necrox-5 methanesulfonate
561380NecroX-5 mesylate
A19633-2NecroX-5 2mg
A19633-5NecroX-5 5mg
A19633-100NecroX-5 100mg
A19633-1NecroX-5 1mg
A19633-50NecroX-5 50mg
A19633-10NecroX-5 10mg
A19633-25NecroX-5 25mg

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