JBIR-22

• Description :

  JBIR-22 is a protein-protein interaction inhibitor of proteasome assembly factor 3 homodimer, which has the activity of inhibiting this interaction and exerting long-term cytotoxicity against human cervical cancer cell lines, and its stereochemical structure has been determined by total synthesis.

• UNSPSC :

  12352005

• Target :

  Proteasome

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Others

• Smiles :

  O/C([C@@H]1[C@]2([H])[C@@](CCCC2)([H])C=C[C@@H]1C)=C3C([C@@H](N(C\3=O)C)C[C@](C(O)=O)(O)C(C)C)=O

• Molecular Formula :

  C23H33NO6

• Molecular Weight :

  419.51

• References & Citations :

  [1]JBIR-22, an inhibitor for protein-protein interaction of the homodimer of proteasome assembly factor 3|[2]Stereochemical Assignment of the Protein-Protein Interaction Inhibitor JBIR-22 by Total Synthesis

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1219095-76-7]