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ETC-159

CAT: 0804-HY-18988-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-18988-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ETC-159 (ETC-1922159) is a potent, orally available PORCN inhibitor. ETC-159 inhibits β-catenin reporter activity with an IC50 of 2.9 nM.
CAS Number
[1638250-96-0]
Product Name Alternative
ETC-1922159
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Porcupine; Wnt
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ETC-159.html
Concentration
10mM
Purity
99.13
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=C(C2=CC=CC=C2)N=N1)CN3C=NC4=C3C(N(C)C(N4C)=O)=O
Molecular Formula
C19H17N7O3
Molecular Weight
391.38
Precautions
H302, H315, H319, H335
References & Citations
[1]Madan B, et al. Wnt addiction of genetically defined cancers reversed by PORCN inhibition. Oncogene. 2015 Aug 10. doi: 10.1038/onc.2015.280.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1

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M17355-01ETC-159
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A15840-5ETC-159 5mg
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