RRD-251

• Product Name Alternative:

  SR1378, 7-Deazaadenosine

• UNSPSC Description:

  RRD-251 is an inhibitor of retinoblastoma tumor suppressor protein (Rb)-Raf-1 interaction, with potent anti-proliferative, anti-angiogenic and anti-tumor activities[1].

• Target Antigen:

  Apoptosis; Raf

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;MAPK/ERK Pathway

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/rrd-251.html

• Purity:

  99.94

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  NC(SCC1=CC=C(Cl)C=C1Cl)=N.[H]Cl

• Molecular Weight:

  271.59

• References & Citations:

  [1]Sandeep Singh, et al. Rb-Raf-1 interaction disruptor RRD-251 induces apoptosis in metastatic melanoma cells and synergizes with dacarbazine. Mol Cancer Ther. 2010 Dec; 9(12): 3330–3341.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  72214-67-6