MK-251

• Description :

  MK-251 is an orally active anti-arrhythmic agent. MK-251 prevents or modifies ventricular arrhythmias induced in dogs and baboons by tetrafluorethylbutylamine. MK-251 antagonizes the arrhythmias caused by Digoxin (HY-B1049) in cats. MK-251 at effective doses has little effect on basic cardiovascular parameters such as blood pressure, cardiac output, myocardial contractility and ventricular conduction, thus demonstrating its unique advantages[1].

• CAS Number :

  [36386-71-7]

• UNSPSC :

  12352005

• Target :

  Others

• Related Pathways :

  Others

• Field of Research :

  Cardiovascular Disease

• Smiles :

  FC(C1=CC=CC=C1)(C(F)(C2=CC=C(C(C)(C)N)C=C2)F)F

• Molecular Formula :

  C17H17F4N

• Molecular Weight :

  311.32

• References & Citations :

  [1]Torchiana ML, et al. The antiarrhythmic and hemodynamic actions of alpha, alpha-dimethyl-4- (alpha, alpha, beta, beta-tetrafluorophenethyl) benzylamine (MK-251) . J Pharmacol Exp Ther. 1975 Aug;194 (2) :415-26.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported