Zopiclone N-oxide

• UNSPSC Description:

  Zopiclone N-oxide (RP 29753) is a less active metabolite of Zopiclone. Zopiclone N-oxide is also an impurity of Eszopiclone and is formed by the oxidation of Eszopiclone[1][2].

• Target Antigen:

  Drug Metabolite; GABA Receptor

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/zopiclone-n-oxide.html

• Purity:

  98.0

• Solubility:

  DMSO : 16.67 mg/mL (ultrasonic)

• Smiles:

  O=C(N1CC[N+](C)([O-])CC1)OC2N(C3=NC=C(Cl)C=C3)C(C4=NC=CN=C42)=O

• Molecular Weight:

  404.81

• References & Citations:

  [1]C Fernandez, et al. Pharmacokinetics of zopiclone and its enantiomers in Caucasian young healthy volunteers. Drug Metab Dispos. Nov-Dec 1993;21(6):1125-8.|[2]Yu Sha, et al. Synthesis of RP 48497, an impurity of eszopiclone. Molecules. 2008 Aug 22;13(8):1817-21.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  43200-96-0