Abiraterone N-oxide

• UNSPSC Description:

  Abiraterone N-oxide is a metabolite of Abiraterone (HY-148377). Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity[1].

• Target Antigen:

  Drug Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/abiraterone-n-oxide.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@@]12[C@](CC=C2C3=C[N+]([O-])=CC=C3)([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H](CC5)O)=CC4)C)([H])CC1

• Molecular Weight:

  365.51

• References & Citations:

  [1]Hu Y, Huang J, et al. Simultaneous determination of abiraterone and its five metabolites in human plasma by LC-MS/MS: Application to pharmacokinetic study in healthy Chinese subjects. J Pharm Biomed Anal. 2022 Aug 5;217:114826.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2378463-76-2