Products for Research Use Only
RegisterLogin

10-Methoxycamptothecin (Standard)

CAT: 0804-HY-N0446RSize: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N0446RSize:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
10-Methoxycamptothecin (Standard) is the analytical standard of 10-Methoxycamptothecin. This product is intended for research and analytical applications. 10-Methoxycamptothecin is a natural bioactive derivative of camptothecin (CPT) isolated from Camptotheca acuminata, and has been confirmed to possess high anti-cancer properties. 10-Methoxycamptothecin has higher cytotoxicity than 10-hydroxycamptothecin by testing antitumor activity against 2774 cell lines[1].
CAS Number
19685-10-0
UNSPSC
12352005
Target
ADC Payload; Reference Standards
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/10-methoxycamptothecin-standard.html
Smiles
O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=CC(OC)=CC=C5N=C4C3=C2)=O
Molecular Formula
C21H18N2O5
Molecular Weight
378.38
References & Citations
[1]Zheng J, et al. Development and validation of a RP-HPLC method with fluorescence detection for simultaneous determination of 10-methoxycamptothecin and its metabolite 10-hydroxycamptothecin in rat plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Aug 15;903:81-7.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Chemical Information

10-Methoxycamptothecin

10-Methoxycamptothecin has been reported in Camellia sinensis, Perilla frutescens, and other organisms with data available.

CAS Number19685-10-0
PubChem CID97283
IUPAC Name(19S)-19-ethyl-19-hydroxy-7-methoxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
Molecular FormulaC21H18N2O5
Molecular Weight378.4
XLogP1
Topological Polar Surface Area89
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Heavy Atom Count28
Formal Charge0
Complexity790
SMILES
CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)OC)O
InChI
InChI=1S/C21H18N2O5/c1-3-21(26)15-8-17-18-12(6-11-7-13(27-2)4-5-16(11)22-18)9-23(17)19(24)14(15)10-28-20(21)25/h4-8,26H,3,9-10H2,1-2H3/t21-/m0/s1
InChIKey
KLFJSYOEEYWQMR-NRFANRHFSA-N
Chemical Structure
2D Structure
2D structure of 10-Methoxycamptothecin
CAS: 19685-10-0
CID: 97283
Formula: C21H18N2O5
MW: 378.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight378.4
XLogP31
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass378.12157168
Monoisotopic Mass378.12157168
Topological Polar Surface Area89 Ų
Heavy Atom Count28
Formal Charge0
Complexity790
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-N0446-0110-Methoxycamptothecin
HY-N6011-019-Methoxycamptothecin
HY-N0275R(±) -10-Hydroxycamptothecin (Standard)
HY-N2434R[10]-Shogaol (Standard)
HY-N0448R-0110-Gingerol (Standard)
HY-N1391R10-Deacetyltaxol (Standard)
HY-W018829R10-Undecenal (Standard)
HY-Z4484RAnastrozole impurity 10 (Standard)
HY-Z1906RDabigatran impurity 10 (Standard)
HY-W009754R-01Antidepressant agent 10 (Standard)

Alternative Products

CatalogName
A3611PH 10.0 Standard
GARD10Reagecon Gardner 10 Colour Standard
TB003 00100Turbidity Standard Solution 10 NTU
SAYN105Reagecon Saybolt -10 Colour Standard
PH-BUFF10-500PH 10 Buffer Standard 500mL
F1078H-1JSR A+ Standard H (10 ng)
CALMIX10-100-01ICP Instrument Check Standard 10
WAT1556Hanna Calibration Standard 10 FTU
SCL010Reagecon Chloride Standard 10 ppm
31423Kylt® Influenzavirus A Standard LD 10

Popular Products