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TRAIL/Apo2L

CAT: 0209-102-PA11SSize: 100 µgDry Ice: NoHazardous: No
CAT#:0209-102-PA11SSize:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TNF-related apoptosis-inducing ligand (TRAIL) is a ligand molecule which induces apoptosis. It is a type II transmembrane protein with homology to other members of the tumor necrosis factor family. In humans, the gene that encodes for TRAIL is located at chromosome 3q26. TRAIL binds to the death receptors, DR4 and DR5. The process of apoptosis is caspase-8-dependent. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues.
Synonyms
TNFSF10; TL2; APO2L; CD253; TRAIL; Apo-2L
NCBI Gene ID
8743
UniProt
P50591
Accession Number
NP_003801.1
Accession Number mRNA
NM_003810.3
Chromosomal Location
3q26
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human TRAIL/ApoL2
Clone
Rabbit IgG
Applications
WB
Purification Method
Protein-A purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized from PBS
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
Host or Source
Rabbit

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