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CD257/BAFF/TNFSF13B

CAT: 0544-MBS439850-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
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CAT#:0544-MBS439850-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[CD257]
NCBI Gene ID
10673
Reactivity
Human. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 °C.
Antibody without azide - store at -20 to -80 °C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
BAFF/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-gamma and down-regulated by PMA/ionomycin treatment. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors; BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3).
Other Gene Names
[TNFSF13B; TNFSF13B; DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNLG7A; TNFSF20; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; BLyS; TALL-1]
Short Name
[CD257/BAFF/TNFSF13B]
Other Product Names
[tumor necrosis factor ligand superfamily member 13B isoform 2; Tumor necrosis factor ligand superfamily member 13B; tumor necrosis factor ligand superfamily member 13B; TNF superfamily member 13b; B lymphocyte stimulator; BLyS]
NCBI GI Number
224548983
NCBI Accession Number
NP_001139117.1
NCBI GB Accession Number
NM_001145645.2
Uniprot Accession Number
Q9Y275

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