TNFRSF11A

CAT: 0209-101-M850Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-101-M850Size:100 µg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RANK (receptor activator of NF-kappa B, also known as TRANCE receptor, osteoclast differentiation factor receptor [ODFR]) and TNFRSF11A is a member of the tumor necrosis factor receptor family. The full-length human RANK cDNA encodes a type I transmembrane protein of 616 amino acids with a predicted 184 amino acid extracellular domain and a 383 amino acid cytoplasmic domain. The extracellular domain contains two potential N-linked glycosylation sites. RANK shares significant amino acid homology with other members of the TNF R family in its extracellular four cysteine-rich repeats. RANK is widely expressed with highest levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. RANK is expressed in dendritic cells.
Synonyms
Tumor necrosis factor receptor superfamily member 11A, Osteoclast differentiation factor receptor (ODFR), Receptor activator of NF-KB, CD265
NCBI Gene ID
8792
UniProt
Q9Y6Q6
Accession Number
NP_003830.1
Accession Number mRNA
NM_003839.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant TNFRSF11A
Clone
(#7G22)
Applications
WB, IHC (P)
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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