RegisterLogin

TIMP-2

CAT: 0209-101-M838Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-101-M838Size:100 µg
Selected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIMP-1 and TIMP-2 binds to the hemopexin- like domain of pro-MMP-9 and pro-MMP-2, respectively. The latter binding is essential for the cell surface activation of MMP-2 by MMP-14.
Synonyms
TIMP2; CSC-21K
NCBI Gene ID
7077
UniProt
P16035
Accession Number
NP_003246
Accession Number mRNA
NM_003255
Chromosomal Location
17q25
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant TIMP-2 protein
Clone
(#2C64)
Applications
Capture Ab
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

Related Products

CatalogName
100-430-L50TIMP-1
101-M871TIMP-3
100-430TIMP-1
100-430STIMP-1
103-M277TIMP-1
101-M125TIMP-3
101-M126TIMP-4
102-P252TIMP-1
101-M123TIMP-1
100-430-L1000TIMP-1

Alternative Products

CatalogName
553900TIMP-2
E8RT1617TIMP-2
MBS8535195-01TIMP-2
MBS692703-01TIMP-2
515040TIMP-2 discontinued
V3344SAF-100UGTIMP-2 Antibody
V3344-100UGTIMP-2 Antibody
MBS9435197-01TIMP-2 Antibody
48343-01TIMP-2 Antibody
250884TIMP-2 Antibody

Popular Products