RegisterLogin

Synuclein alpha

CAT: 0209-500-095SSize: 5 µgDry Ice: NoHazardous: No
CAT#: 500-095SSize: 5 µg
Selected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Alpha-Synuclein is a member of the Synuclein family. It is expressed principally in brain but also expressed in low concentrations in all tissues except liver. Alpha synuclein interacts with UCHL1, Phospholipase D and histones. In addition, alpha synuclein is an important regulatory component of vesicular transport in neuronal cells. It has been suggested that alpha synuclein is related to the pathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in its action will lead to Dementia Lewy Body (DLB) . Mouse Alpha-Synuclein, is also known as Non-A Beta Component of AD Amyloid, Non-A4 Component of Amyloid Precursor, NACP, SNCA, NACP, PARK1. Recombinant mouse alpha-Synuclein is produced by our E.coli expression system and the target gene encoding Met1-Ala140 is expressed, and purified as periplasmic protein by ion-exchange chromatography
Synonyms
Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor (NACP
NCBI Gene ID
20617
UniProt
O55042
Accession Number
NP_001035916.1
Accession Number mRNA
NM_001042451.2
Reactivity
Mouse
Sequence
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVTTVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGNIAAATGFVKKDQMGKGEEGYPQEGILEDMPVDPGSEAYEMPSEEGYQDYEPEA
Assay Protocol
Always centrifuge tubes before opening. Dissolve the lyophilized protein in ddH2O. Mix gently and do not mix by vortex. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
>95% as determined by SDS-PAGE
Bioactivity
Not tested
Length
140
Reconstitution
Water
Molecular Weight
14.4 kDa
Host or Source
E. coli
N Terminal Sequence
MDVFMKGLSK

Related Products

CatalogName
M10-081-L500RELM alpha
M10-081-L1000RELM alpha
100-098-L250SCGF-alpha
100-098-L500SCGF-alpha
100-098-L1000SCGF-alpha
M10-041-L250TNF-alpha
M10-041-L500TNF-alpha
R20-013-L100TNF-alpha
R20-013-L500TNF-alpha
100-103TGF-alpha

Alternative Products

CatalogName
216047Synuclein, alpha (Alpha-Synuclein)
216045Synuclein, alpha (Alpha-Synuclein)
216044Synuclein, alpha (Alpha-Synuclein)
216046Synuclein, alpha (Alpha-Synuclein)
367849Synuclein, alpha (alpha Synuclein, Synuclein) (Not for Export EU)
216969Synuclein, alpha (Synuclein-alpha, SNCA)
MBS8534935-01Alpha-Synuclein
052303Synuclein, alpha
AP78879-01Alpha-synuclein
528798-01Synuclein-alpha

Popular Products