SRY Recombinant Protein

SRY Recombinant Protein

• Description: The „Sex determining region of Y-Gen” (SRY), known as SRY gene, is coding for a transkription factor (TDF for Testis-determining factor). It belongs to the protein family of DNA binding-proteins. The SRY gene is beside other genes used for the determination of the sex in human as well as other mammals. Most mammals have for this purpose a further gene, UBE1. In humans SRY is normally located on the short arm of the Y chromosome. Accordingly, people who possess this chromosome with the corresponding gene, normally have a male phenotype. It does not matter how many copies of the X chromosome are present, even people with a multiple X chromosome (Klinefelter's syndrome) have this. The protein encoded by the gene Testis-determining factor controls the development of male sex
• Synonyms: Sex-determining region Y protein; Testis-determining factor
• CAS Number: 9000-83-3
• NCBI Gene ID: 280931
• UniProt: Q03255
• Accession Number: NP_001014407.1
• Accession Number mRNA: NM_001014385.1
• Host: E. coli
• Origin Species: Bovine
• Species Reactivity: Bovine
• Sequence: MFRVLNDDVYSPAVVQQQTTLAFRKDSSLCTDSHSANDQCERGEHVRESSQDHVKRPMNAFIVWSRERRRKVALENPKMKNSDISKQLGYEWKRLTDAEKRPFFEEAQRLLAIHRDKYPGYKYRPRRRAKRPQKSLPADSSILCNPMHVETLHPFTYRDGCAKTTYSQMESQLSRSQSVIITNSLLQKEHHSSWTSLGHNKVTLATRISADFPCNKSLEPGLSCAYFQYLE
• Detection Range: Data not available.
• Purity: > 90% by SDS-PAGE
• Length: 231
• Form: Lyophilized
• Buffer: water
• Reconstitution: Centrifuge vial prior to opening. Bovine SRY should be reconstituted in PBS to a concentration of 0.1 mg/ml. This solution can be diluted in water or other buffered solutions.
• Molecular Weight: 26.8 kDa
• Shipping Conditions: Room Temperature
• Storage Conditions: The lyophilized powder although stable at room temperature for 3 weeks, is best stored desiccated at -20°C. Reconstituted bo SRY should be stored in working aliquots at -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).