LIGHT Recombinant Protein

LIGHT Recombinant Protein

• Description: LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFkB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant murine LIGHT is a 20.1 kDa protein containing 183 amino acid residues.
• Synonyms: Tnfsf14; LTg; HVEML; LIGHT; Ly113; HVEM-L; LIGHT; tumor necrosis factor (ligand) superfamily, member 14
• CAS Number: 9000-83-3
• NCBI Gene ID: 50930
• UniProt: Q9QYH9
• Accession Number: NP_062291
• Accession Number mRNA: NM_019418
• Gene Location: 17; 17 D-E1
• Host: E. coli
• Origin Species: Mouse
• Species Reactivity: Human, Mouse
• Sequence: MRLHQRLGDI VAHLPDGGKG SWEKLIQDQR SHQANPAAHL TGANASLIGI GGPLLWETRL GLAFLRGLTY HDGALVTMEP GYYYVYSKVQ LSGVGCPQGL ANGLPITHGL YKRTSRYPKE LELLVSRRSP CGRANSSRVW WDSSFLGGVV HLEAGEEVVV RVPGNRLVRP RDGTRSYFGA FMV
• Detection Range: Testing in progress.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 183
• Form: Lyophilized
• Molecular Weight: 20.1 kDa
• Shipping Conditions: Room Temperature