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Semaphorin 6C

CAT: 0209-101-M625Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M625Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The Semaphorins make up the largest family of axon guidance cues yet described. Semaphorins are divided into 8 classes (classes 3-7 found in vertebrates) . Class 3 Semaphorins are secreted, classes 4 through 6 are transmembrane proteins, and class 7 are membrane associated via glycosylphosphatidylinositol (GPI) linkage. They are characterized structurally by a conserved ~400 amino acid sema domain. They are classically described as collapsing factors and mediators of axon repulsion, although they may also act as context-dependent chemoattractants. Semaphorins have been shown to have roles in cardiovascular development and in the regulation of immune cell antigen presentation. Receptors or receptor complexes that mediate semaphorin signaling include proteins of the Neuropilin and Plexin families.
Synonyms
SEMA6C; SEMAY; m-SemaY; m-SemaY2
NCBI Gene ID
10500
UniProt
Q9H3T2
Accession Number
NP_001171532.1
Accession Number mRNA
NM_001178061.1
Chromosomal Location
1q21.2
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human Semaphorin 6C EC domain
Clone
(#9S21)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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Alternative Products

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