Semaphorin 3C

CAT: 0209-101-M721Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-101-M721Size:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Semaphorins are a large group of structurally related secreted, GPI-anchored and transmembrane cell signaling molecules. There are 8 major classifications (1-7) of Semaphorins characterized by the existence of a conserved 500 amino acid SEMA domain at the amino terminus. Classes 3,4,6, and 7 are found in vertebrates only, whilst class 5 is found in both vertebrates and invertebrates. Each class is then divided into additional subgroups based on shared structural characteristics. Semaphorins primarily function as axon growth cone guidance factors during neuronal development. Semaphorin 3A acts as a chemo-repellent to axons, and an inhibitor of the growth of axons by signaling through receptors, Neuropilin-1and Plexin-A. Recombinant human Semaphorin 3A is a 751 amino acid protein containing the SEMA domain, an immunoglobulin c2-like domain and a basic domain (Arg/Lys rich) near the C-terminus.
Synonyms
Sema3c; SemE; Semae; 1110036B02Rik
NCBI Gene ID
10512
UniProt
Q99985
Accession Number
NP_006370.1
Accession Number mRNA
NM_006379.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human Semaphorin 3C
Clone
(#29U11)
Applications
WB, IHC
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

Related Products

CatalogName
101-M625Semaphorin 6C
101-M624Semaphorin 6A
103-M464Semaphorin 6B
101-M626Semaphorin 7A
100-151-L500Semaphorin 3A
103-M463Semaphorin 6A
100-151-L100Semaphorin 3A
100-151SSemaphorin 3A
100-151Semaphorin 3A
101-M722Semaphorin 6B

Alternative Products

CatalogName
MBS6008810-01Semaphorin 3G (Semaphorin-3G, SEMA3G, Semaphorin Sem2)
S0668-57ESemaphorin 5A (Semaphorin-5A, Semaphorin F, Sema F, SEMA5A, SEMAF)
MBS627660-01Semaphorin 5A (Semaphorin-F, Sema F, Semaphorin-5A, SEMAF, SEMA5A)
MBS648737-01Semaphorin 6D (Semaphorin-6D, SEMA6D, KIAA1479)
MBS649637-01Semaphorin 4G (Semaphorin-4G, SEMA4G, KIAA1619)
MBS8578322-01Semaphorin 5A
AP87565-01Semaphorin-7A
AP87439-01Semaphorin-3B
AP87581-01Semaphorin-4D
MBS2889498Semaphorin-3A

Popular Products