Semaphorin 7A

CAT: 0209-101-M626Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-101-M626Size:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
The Semaphorins make up the largest family of axon guidance cues yet described. Semaphorins are divided into 8 classes (classes 3-7 found in vertebrates) . Class 3 Semaphorins are secreted, classes 4 through 6 are transmembrane proteins, and class 7 are membrane associated via glycosylphosphatidylinositol (GPI) linkage. They are characterized structurally by a conserved ~400 amino acid sema domain. They are classically described as collapsing factors and mediators of axon repulsion, although they may also act as context-dependent chemoattractants. Semaphorins have been shown to have roles in cardiovascular development and in the regulation of immune cell antigen presentation. Receptors or receptor complexes that mediate semaphorin signaling include proteins of the Neuropilin and Plexin families.
Synonyms
SEMA7A; JMH; CD108; SEMAL; CDw108; SEMAK1; H-Sema-L; H-SEMA-K1
NCBI Gene ID
8482
UniProt
O75326
Accession Number
NP_003603.1
Accession Number mRNA
NM_003612.3
Chromosomal Location
15q22.3-q23
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human Semaphorin 6C EC domain
Clone
(#99D22)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

Related Products

CatalogName
100-129-L100Wnt-7a
100-129Wnt-7a
100-129-L500Wnt-7a
100-129SWnt-7a
100-151-L100Semaphorin 3A
100-151SSemaphorin 3A
100-151Semaphorin 3A
101-M721Semaphorin 3C
101-M625Semaphorin 6C
103-M462Semaphorin 3C

Alternative Products

CatalogName
133100Semaphorin 3G (Semaphorin-3G, SEMA3G, Semaphorin Sem2)
S0668-57GSemaphorin 5A (Semaphorin-5A, Semaphorin F, Sema F, SEMA5A, SEMAF)
MBS627660-01Semaphorin 5A (Semaphorin-F, Sema F, Semaphorin-5A, SEMAF, SEMA5A)
133106Semaphorin 4G (Semaphorin-4G, SEMA4G, KIAA1619)
133110Semaphorin 6D (Semaphorin-6D, SEMA6D, KIAA1479)
AP79788-01Semaphorin-3E
AP87440-01Semaphorin-3F
216930Semaphorin 6C
AP89474Semaphorin-3G
AP87964Semaphorin-3C

Popular Products