Semaphorin 3C

CAT: 0209-103-M462Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-103-M462Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The Semaphorins make up the largest family of axon guidance cues yet described. Semaphorins are divided into 8 classes (classes 3-7 found in vertebrates) . Class 3 Semaphorins are secreted, classes 4 through 6 are transmembrane proteins, and class 7 are membrane associated via glycosylphosphatidylinositol (GPI) linkage. They are characterized structurally by a conserved ~400 amino acid sema domain. They are classically described as collapsing factors and mediators of axon repulsion, although they may also act as context-dependent chemoattractants. Semaphorins have been shown to have roles in cardiovascular development and in the regulation of immune cell antigen presentation. Receptors or receptor complexes that mediate semaphorin signaling include proteins of the Neuropilin and Plexin families.
Synonyms
Sema3c; SemE; Semae; 1110036B02Rik
NCBI Gene ID
20348
UniProt
Q62181
Accession Number
NP_038685.3
Accession Number mRNA
NM_013657.5
Chromosomal Location
5 A3; 5
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse Semaphorin 3C
Clone
(#7F18)
Applications
WB
Purification Method
Protein A/G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

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Alternative Products

CatalogName
MBS6008810-01Semaphorin 3G (Semaphorin-3G, SEMA3G, Semaphorin Sem2)
S0668-57ESemaphorin 5A (Semaphorin-5A, Semaphorin F, Sema F, SEMA5A, SEMAF)
MBS627660-01Semaphorin 5A (Semaphorin-F, Sema F, Semaphorin-5A, SEMAF, SEMA5A)
MBS648737-01Semaphorin 6D (Semaphorin-6D, SEMA6D, KIAA1479)
MBS649637-01Semaphorin 4G (Semaphorin-4G, SEMA4G, KIAA1619)
MBS8578322-01Semaphorin 5A
AP87565-01Semaphorin-7A
AP87439-01Semaphorin-3B
AP87581-01Semaphorin-4D
MBS2889498Semaphorin-3A

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