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SDF-1 beta (CXCL12)

CAT: 0209-M10-085Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0209-M10-085Size:10 µg
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Description
SDF-1α and β are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant murine SDF-1β is a 8.5 kDa protein containing 72 amino acid residues.
Synonyms
Pxorf31
NCBI Gene ID
912189
UniProt
P40224
Accession Number
NP_068350.1
Accession Number mRNA
NM_021704
Chromosomal Location
6 F1; 6 53.0 cM
Reactivity
Mouse
Cross Reactivity
Human, Mouse
Sequence
KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRL KM
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract human monocytes using a concentration range of 50.0-100.0 ng/ml.
Length
72
Form
Lyophilized
Molecular Weight
8.5 kDa
Host or Source
E. coli

UniProtKB · P40224

Stromal cell-derived factor 1

SDF1_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P40224
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Cxcl12
Protein existence
2: Evidence at transcript level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
SDF-1
EC number
—
Processing
Precursor
Secondary accessions
Q4FJL5, Q543V6
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

Chemotaxis

Molecular function

CytokineGrowth factor

PTM

Disulfide bond

Technical term

Reference proteome

Cellular component

Secreted

Domain

Signal

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MBS691879-01Mouse SDF-1 beta (CXCL12)
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