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Netrin-4

CAT: 0209-101-M577Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M577Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Netrins have been identified as midline-derived chemoattractants that guide axons to the midline during development. Netrins are antagonized by Slit and Robo proteins which compete for DCC (deleted in colorectal cancer) receptor binding. Netrins also have axon repulsion effects when interacting with the UNC5 (uncoordinated-5) receptor family, either alone or with DCC receptors. Netrins are a laminin-related family of matrix-binding secreted proteins containing an N-terminal laminin gamma-chain-related globular domain (domain VI), three laminin EGF-like repeats, and a C-terminal heparin-binding domain.
Synonyms
NTN4; PRO3091
NCBI Gene ID
59277
UniProt
Q9HB63
Accession Number
NP_067052.2
Accession Number mRNA
NM_021229.3
Chromosomal Location
12q22
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
EC domain of human recombinant Netrin-4
Clone
(#9H27)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2