MCP-4 (CCL13) Recombinant Protein

• Description:

  The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross- reacts across species. Recombinant murine MCP-2 is an 8.6 kDa protein containing 75 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

• Synonyms:

  CCL13; NCC1; CKb10; MCP-4; NCC-1; SCYL1; SCYA13

• CAS Number:

  9000-83-3

• NCBI Gene ID:

  6357

• UniProt:

  Q99616

• Accession Number:

  NP_005399

• Accession Number mRNA:

  NM_005408

• Gene Location:

  17q11.2

• Host:

  E. coli

• Origin Species:

  Human

• Species Reactivity:

  Monkey, Mouse, Human, Leech

• Sequence:

  QPDALNVPST CCFTFSSKKI SLQRLKSYVI TTSRCPQKAV IFRTKLGKEI CADPKEKWVQ NYMKHLGRKA HTLKT

• Detection Range:

  Determined by its ability to chemoattract human monocytes using a concentration of 10.0-100.0 ng/ml.

• Endotoxin:

  < 0.1 ng/µg of protein (<1EU/µg)

• Purity:

  > 98% by SDS-PAGE & HPLC analyses

• Length:

  75

• Form:

  Lyophilized

• Molecular Weight:

  8.6 kDa

• Shipping Conditions:

  Room Temperature