MCP-3 (CCL7) Recombinant Protein

• Description:

  The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross- reacts across species. Recombinant murine MCP-3 is an 8.5 kDa protein containing 74 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

• Synonyms:

  Ccl7; fic; marc; mcp3; MCP-3; Scya7

• CAS Number:

  9000-83-3

• NCBI Gene ID:

  20306

• UniProt:

  Q03366

• Accession Number:

  NP_038682.1

• Accession Number mRNA:

  NM_013654.3

• Gene Location:

  11 C; 11 46.5 cM

• Host:

  E. coli

• Origin Species:

  Mouse

• Species Reactivity:

  Mouse, Human

• Sequence:

  QPDGPNASTC CYVKKQKIPK RNLKSYRRIT SSRCPWEAVI FKTKKGMEVC AEAHQKWVEE AIAYLDMKTP TPKP

• Detection Range:

  Determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 10.0-100.0 ng/ml.

• Endotoxin:

  < 0.1 ng/µg of protein (<1EU/µg)

• Purity:

  > 98% by SDS-PAGE & HPLC analyses

• Length:

  74

• Form:

  Lyophilized

• Molecular Weight:

  8.5 kDa

• Shipping Conditions:

  Room Temperature