MCP-3 (CCL7) Recombinant Protein

MCP-3 (CCL7) Recombinant Protein

• Description: The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross- reacts across species. Recombinant human MCP-3 is a 9.0 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
• Synonyms: CCL7; FIC; MARC; MCP3; NC28; MCP-3; SCYA6; SCYA7
• CAS Number: 9000-83-3
• NCBI Gene ID: 6354
• UniProt: P80098
• Accession Number: NP_006264
• Accession Number mRNA: NM_006273
• Gene Location: 17q11.2-q12
• Host: E. coli
• Origin Species: Human
• Species Reactivity: Hamster, Monkey, Mouse, Human
• Sequence: QPVGINTSTT CCYRFINKKI PKQRLESYRR TTSSHCPREA VIFKTKLDKE ICADPTQKWV QDFMKHLDKK TQTPKL
• Detection Range: Determined by its ability to chemoattract BaF3 cells expressing human CCR2 receptor using a concentration range of 300-500 ng/ml.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 76
• Form: Lyophilized
• Molecular Weight: 9 kDa
• Shipping Conditions: Room Temperature