KC (CXCL1)

• Description:

  The predicted amino acid sequence of the mouse KC gene product indicates KC is a member of the CXC subfamily of chemokines. The protein sequence of mouse KC shows approximately 63% identity to that of mouse MIP-2. In addition, the protein sequence of KC is approximately 60% identical to the human GROs. It has been suggested that mouse KC and MIP-2 are the homologs of the human GROs and rat CINCs. KC mRNA is expressed in macrophages, endothelial cells, and fibroblasts. The rat chemokines CINC (cytokine-induced neutrophil chemoattractant) -1, CINC-2 alpha, CINC-2 beta and CINC-3 constitute a group of rat CXC chemokines that show significant sequence similarity to human GROs and mouse MIP-2 and KC.

• Synonyms:

  CXCL1

• NCBI Gene ID:

  14825

• UniProt:

  P12850

• Accession Number:

  NP_032202.1

• Accession Number mRNA:

  NM_008176.3

• Chromosomal Location:

  5 E-F; 5 51.0 cM

• Reactivity:

  Anti-Mouse

• Cross Reactivity:

  Mouse

• Target Antigen:

  Recombinant mouse KC (CXCL1)

• Clone:

  Rabbit IgG

• Applications:

  ELISA, WB

• Purification Method:

  Antigen-affinity purified

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

• Form:

  Lyophilized from PBS

• Buffer:

  PBS

• Reconstitution:

  Water

• Storage Conditions:

  The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.

• Host or Source:

  Rabbit