GRO-alpha/MGSA (CXCL1)

• Description:

  Human GRO alpha (also known as MGSA) promotes neutrophil chemotaxis and degranulation. It also stimulates mitogenesis in certain human melanoma cells. Human GROa is a 7.8 kDa protein containing 73 amino acid residues

• Synonyms:

  CXCL1; FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a

• NCBI Gene ID:

  2919

• UniProt:

  P03941

• Accession Number:

  NP_001502.1

• Accession Number mRNA:

  NM_001511.3

• Chromosomal Location:

  4q21

• Reactivity:

  Human

• Cross Reactivity:

  Hamster, Monkey, Mouse, Rat, Human

• Sequence:

  ASVATELRCQ CLQTLQGIHP KNIQSVNVKS PGPHCAQTEV IATLKNGRKA CLNPASPIVK KIIEKMLNSD KSN

• Endotoxin:

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity:

  > 98% by SDS-PAGE & HPLC analyses

• Bioactivity:

  Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-50.0 ng/ml.

• Length:

  73

• Form:

  Lyophilized

• Molecular Weight:

  7.8 kDa

• Host or Source:

  E. coli