CXCL1 (GRO alpha)

• Description:

  Cotton rat growth-regulatedprotein (GRO) is a member of the ELR+ CXC subfamily of chemokines. The cotton rat GRO cDNA encodes a 100 amino acid (aa) precursor protein with a 27 aa putative signal peptide and a 73 aa mature protein. The predicted amino acid sequence of the mouse KC gene product indicates KC is a member of the CXC subfamily of chemokines. The protein sequence of mouse KC shows approximately 63% identity to that of mouse MIP-2. In addition, the protein sequence of KC is approximately 60% identical to the human GROs. It has been suggested that mouse KC and MIP-2 are the homologs of the human GROs and rat CINCs. KC mRNA is expressed in macrophages, endothelial cells, and fibroblasts.

• Synonyms:

  CXCL1; FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a

• NCBI Gene ID:

  2919

• UniProt:

  P09341

• Accession Number:

  NP_001502.1

• Accession Number mRNA:

  NM_001511.2

• Chromosomal Location:

  4q21

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Human recombinant CXCL1

• Clone:

  (#9A18)

• Applications:

  WB, N

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG2