Products for Research Use Only
RegisterLogin

Integrin alpha M

CAT: 0209-103-M27Size: 50 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0209-103-M27Size:50 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Integrins are transmembrane proteins that mediate interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM) . Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metastatic and invasive potential of tumor cells. They exist as heterodimers consisting of alpha and beta subunits. Some alpha and beta subunits exhibit specificity for one another and may be designated as a VLA (very late antigen) member. Heterodimers often preferentially bind certain cell adhesion molecules, or constituents of the ECM. Although they have no catalytic activity, integrins can be part of multimolecular signaling complexes known as focal adhesions.
Synonyms
ITGAM
NCBI Gene ID
16409
UniProt
P05555
Accession Number
NP_001076429.1
Accession Number mRNA
NM_001082960.1
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse Integrin alpha M
Clone
(#4A24)
Applications
IHC, ICC, FC
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

UniProtKB · P05555

Integrin alpha-M

ITAM_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P05555
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Itgam
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q8CA73
Protein keywords

Technical term

3D-structureDirect protein sequencingReference proteome

Coding sequence diversity

Alternative splicing

Ligand

CalciumMetal-binding

Biological process

Cell adhesion

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoprotein

Molecular function

IntegrinReceptor

Domain

RepeatSignalTransmembraneTransmembrane helix

Related Products

CatalogName
101-M519Integrin alpha 6
101-M515Integrin alpha 2 (CD49b)
101-M516Integrin alpha 3 (CD49c)
101-M517Integrin alpha 4 (CD49d)
101-M521Integrin alpha V (CD51)
101-M522Integrin alpha X (CD11c)
101-M518Mouse Anti-Human Integrin alpha 5 Monoclonal Antibody
101-M797Mouse Anti-Human Integrin alpha 6 Monoclonal Antibody
101-M523Integrin beta 2 (CD18)
101-M798Integrin beta 3 (CD61)

Alternative Products

CatalogName
208233ITGA11 (Integrin alpha 11, Integrin alpha 11, 4732459H24Rik, Integrin A11, Integrin alpha-11)
MBS6507777-01Integrin alpha 8 (ITGA8, integrin alpha-8)
483758ITGAM (Integrin Alpha-M, integrin Subunit Alpha M)
483756ITGA9 (Integrin Alpha-9, integrin Subunit Alpha 9)
483752ITGA6 (Integrin Alpha-6, Integrin Subunit Alpha 6)
483747ITGA3 (integrin Alpha-3, integrin Subunit Alpha 3)
483744ITGA1 (Integrin Alpha-1, Integrin Subunit Alpha 1)
I7661-36W1Integrin alpha 8 (ITGA8, Integrin alpha-8) (APC)
I7661-36WIntegrin alpha 8 (ITGA8, Integrin alpha-8) (PE)
MBS6507776-01Integrin alpha 8 (ITGA8, Integrin alpha-8)(APC)

Popular Products