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IL-12

CAT: 0209-101-M72Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M72Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Interleukin 12 (IL-12), also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. The IL-12 p40 subunit is shared by IL-23, another heterodimeric cytokine that has biological activities similar to, as well as distinct from, IL-12. IL-12 is produced by macrophages and B cells and has been shown to have multiple effects on T cells and natural killer (NK) cells. While mouse IL-12 is active on both human and mouse cells, human IL-12 is not active on mouse cells.
Synonyms
IL12A; P35; CLMF; NFSK; NKSF1; IL-12A
NCBI Gene ID
3592
UniProt
P29459
Accession Number
NP_000873.2
Accession Number mRNA
NM_000882.3
Chromosomal Location
3q25.33-q26
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human IL-12
Applications
ELISA
Purification Method
Protein A chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized from PBS
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Host or Source
Mouse
Isotype
IgG1

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