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IL-2

CAT: 0209-R20-026Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0209-R20-026Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant rat IL-2ƒ is a 15.3 kDa protein containing 134 amino acid residues.
Synonyms
RbcL
NCBI Gene ID
809853
UniProt
P17108
Accession Number
NP_446288.1
Accession Number mRNA
NM_053836.1
Chromosomal Location
2q25
Reactivity
Rat
Cross Reactivity
Mouse, Rat
Sequence
MAPTSSPAKE TQQHLEQLLL DLQVLLRGID NYKNLKLPMM LTFKFYLPKQ ATELKHLQCL ENELGALQRV LDLTQSKSFH LEDAGNFISN IRVTVVKLKG SENKFECQFD DEPATVVEFL RRWIAIAQSI ISTM
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
The ED50 as determined by the dose-dependent stimulation of the proliferation of murine CTLL-2 cells is < 0.4 ng/ml, corresponding to a specific activity of > 2.5 x 106 units/mg.
Length
134
Form
Lyophilized
Molecular Weight
15.3 kDa
Host or Source
E. coli