IFN beta (Animal Free) Recombinant Protein

CAT:
209-100-191-AF
Size:
20 µg
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
IFN beta (Animal Free) Recombinant Protein - image 1

IFN beta (Animal Free) Recombinant Protein

  • Description:

    Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections.  They also affect cell proliferation and modulate immune responses.  Produced by peripheral blood leukocytes and lymphoblastoid cells, IFN-α is an acid-stable molecule that signals through IFN-α/βR, which is also used by IFN-β.  Both IFNs have similar anti-viral activity and regulate expression of MHC class I antigens.  IFN-α contains four highly conserved cysteine residues that form two disulfide bonds, one of which is necessary for biological activity.  PeproTech’s Recombinant Human IFN-β is a 20.0 kDa protein containing 166 amino acid residues.
  • Synonyms:

    IFNB1; IFB; IFF; IFNB
  • NCBI Gene ID:

    3456
  • UniProt:

    P01574
  • Accession Number:

    NP_002167.1
  • Accession Number mRNA:

    NM_002176
  • Gene Location:

    9p21
  • Host:

    E. coli
  • Origin Species:

    Human
  • Species Reactivity:

    Human, Mouse
  • Sequence:

    MSYNLLGFLQ RSSNFQCQKL LWQLNGRLEY CLKDRMNFDI PEEIKQLQQF QKEDAALTIY EMLQNIFAIF RQDSSSTGWN ETIVENLLAN VYHQINHLKT VLEEKLEKED FTRGKLMSSL HLKRYYGRIL HYLKAKEYSH CAWTIVRVEI LRNFYFINRL TGYLRN
  • Detection Range:

    Determined by its ability to stimulate the proliferation of human TF-1 cells. The expected ED50 is ≤ 0.25 ng/ml, corresponding to a specific activity of ≥ 4 x 106 units/mg.
  • Endotoxin:

    < 0.01 ng/ug of protein (< 0.1 EU/ug)
  • Purity:

    ≥ 95% by SDS-PAGE gel and HPLC analyses.
  • Length:

    166
  • Form:

    Lyophilized
  • Molecular Weight:

    20 kDa
  • Shipping Conditions:

    Room Temperature
  • CAS Number:

    9000-83-3