G-CSFR (CD114)

• Description:

  Human G-CSF R is 836 amino acids (aa) in length, with a 23 aa signal sequence, a 604 aa extracellular region, a 26 aa transmembrane segment, and a 183 aa cytoplasmic domain. As a result of alternative splicing, at least four isoforms of G-CSF R exist that differ in their transmembrane C-terminal region. Human and mouse G-CSF R are 64% identical at the aa level. G-CSF R is expressed in mature neutrophils, neutrophilic precursors, myeloid leukemia cells, and placenta.

• Synonyms:

  CSF3R; CD114; GCSFR

• NCBI Gene ID:

  1441

• UniProt:

  Q99062

• Accession Number:

  NP_000751.1

• Accession Number mRNA:

  NM_000760.3

• Chromosomal Location:

  1p35-p34.3

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Recombinant human G-CSF-R EC domain

• Clone:

  (#8F44)

• Applications:

  WB, FC, Capture Ab

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG1