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G-CSF

CAT: 0209-R20-074-L1000Size: 1000 µgDry Ice: NoHazardous: No
CAT#:0209-R20-074-L1000Size:1000 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Recombinant rat G-CSF is a 21.6 kDa protein consisting of 196 amino acid residues.
Synonyms
Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSFß, pluripoietin
NCBI Gene ID
25610
UniProt
P97712
Accession Number
NP_058800.1
Accession Number mRNA
NM_017104.1
Chromosomal Location
10q31
Reactivity
Rat
Cross Reactivity
Rat
Sequence
MKKIPLLTVS SLPPSLPLPR SFLLKSLEQV RKIQARNTEL LEQLCATYKL CHPEELVLFG HSLGIPKASL SSCSSQALQQ TKCLSQLHSG LFLYQGLLQA LAGISSELAP TLDMLHLDVD NFATTIWQQM ESLGVAPTVQ PTQSTMPIFT SAFQRRAGGV LVTSYLQSFL ETAHHALHHL PRPAQKHFPE SLFISI
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to stimulate the proliferation of mouse NFS-60 cells. The expected ED50 is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.
Length
196
Form
Lyophilized
Molecular Weight
21.6 kDa
Host or Source
E. coli

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