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FGF-acidic (Animal Free)

CAT: 0209-100-016S-AFSize: 10 µgDry Ice: NoHazardous: No
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CAT#:0209-100-016S-AFSize:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant Human FGF-acidic is a 16.8 kDa protein consisting of 141 amino acid residues.
Synonyms
FGF2; BFGF; FGFB; HBGF-2
NCBI Gene ID
2246
UniProt
P05230
Accession Number
NP_000791.1
Accession Number mRNA
NM_000800.4
Chromosomal Location
5q31
Reactivity
Human
Cross Reactivity
Cow, Human, Mouse, Pig, Rat, Shark, Squid
Sequence
MFNLPPGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SVGEVYIKST ETGQYLAMDT DGLLYGSQTP NEECLFLERL EENHYNTYIS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D
Endotoxin
< 0.01 ng/µg of protein (< 0.1 EU/µg)
Purity
≥ 95% by SDS-PAGE gel and HPLC analyses.
Bioactivity
Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.5 ng/ml in the presence of 10 µg/ml heparin, corresponding to a specific activity of ≥ 2 x 106 units/mg.
Length
141
Form
Lyophilized
Molecular Weight
15.8 kDa
Host or Source
E. coli

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Alternative Products

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