FGF acidic

• Description:

  FGF acidic, also known as FGF1, ECGF, and HBGF1, is a 17 kDa non-glycosylated member of the FGF family of mitogenic peptides. FGF acidic, which is produced by multiple cell types, stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis. Alternate splicing generates a truncated isoform of human FGF acidic that consists of the N-terminal 40% of the molecule and functions as a receptor antagonist.

• Synonyms:

  FGF2; BFGF; FGFB; HBGF-2

• NCBI Gene ID:

  2246

• UniProt:

  P05230

• Accession Number:

  NP_000791.1

• Accession Number mRNA:

  NM_000800.4

• Chromosomal Location:

  5q31

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Recombinant human FGF-acidic

• Clone:

  (#7C39)

• Applications:

  WB, IHC

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG2