Fetoprotein alpha

• Description:

  Alpha-Fetal Protein is a protein that in humans is encoded by the AFP gene. The AFP gene is located on the q arm of chromosome 4 (4q25) . AFP is a major plasma protein produced by the yolk sac and the liver during fetal development that is thought to be the fetal form of serum albumin. AFP binds to copper, nickel, fatty acids and bilirubin and is found in monomeric, dimeric and trimeric forms αFetoprotein is a major plasma protein in the fetus. Its concentration is normally low in the adult except when produced by certain tumors.

• Synonyms:

  AFP; FETA; HPAFP; AFP; alpha-fetoprotein; alpha-1-fetoprotein; alpha-fetoglobulin

• NCBI Gene ID:

  174

• UniProt:

  P02771

• Accession Number:

  NP_001125.1

• Accession Number mRNA:

  NM_001134.1

• Chromosomal Location:

  4q11-q13

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Recombinant human alpha-Fetoprotein

• Clone:

  (#7D17)

• Applications:

  WB

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG1